NBR1 Rabbit Polyclonal Antibody, 50ul[BT-AP11720] Biochemical Reagents Mutations in this gene result

Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy

The flamingo cadherins are located at the plasma membrane and have nine cadherin domains

Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus

Alternative promoter usage and alternative splicing result in dozens of transcript variants

BRSK1 plays an essential role in neuronal polarization and may be involved in regulating cell cycle arrest in response to DNA damage

NBR1 Rabbit Polyclonal Antibody, 50ul[BT-AP11720] Biochemical Reagents Mutations in this gene resultThe protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B box coiled coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of