Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Interacts directly with BNIP1/SEC20L and
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Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Interacts directly with BNIP1/SEC20L andInhibits the activity of dimeric NF kappa B REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription (By similarity).
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