PAK gamma(Phospho Ser20) Polyclonal Antibody, 100ul Cell Screening and Imaging Mutations in this gene have

Mutations in this gene have been associated with Krabbe disease| also known as globoid cell leukodystrophy

this protein may signal through receptor serine/threonine kinases

Three distinct forms

Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis

It can be used for affinity chromatography| and then used to separate recombinant| over expressed protein from wild-type protein expressed by the host organism

PAK gamma(Phospho Ser20) Polyclonal Antibody, 100ul Cell Screening and Imaging Mutations in this gene haveThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role