Rab11-FIP1 Polyclonal Antibody, 50ul Mechanical Pipette Duplication of a regulatory region

Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients

Plays a role in TNFSF11-mediated osteoclast differentiation

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

and may act as a cellular antioxidant

LDH family

Rab11-FIP1 Polyclonal Antibody, 50ul Mechanical Pipette Duplication of a regulatory regionRAB11FIP1 (RAB11 family interacting protein 1) encodes one of the Rab11 family interacting proteins (Rab11 FIPs), which play a role in the Rab 11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans Golgi network. Alternative splicing results in multiple