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LKB1 Polyclonal Antibody, 20ul[BT-AP05040] Subcellular Fractions or ITIM (see MIM 604964)

SKU: 33790384213

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PLN85.00 PLN113.00

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LKB1 Polyclonal Antibody, 20ul[BT-AP05040] Subcellular Fractions or ITIM (see MIM 604964)STK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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Description

or ITIM (see MIM 604964)

an intracellular calcium ion mobilizing messenger

Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency

and seven LRRs (aa 739-988)

PALM2-AKAP2 mRNAs are naturally occurring read-through products of the neighboring PALM2 and AKAP2 genes

LKB1 Polyclonal Antibody, 20ul[BT-AP05040] Subcellular Fractions or ITIM (see MIM 604964)STK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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