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Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays The gene encoding ZC3H13 maps

SKU: 33907790032

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Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays The gene encoding ZC3H13 mapsThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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Description

The gene encoding ZC3H13 maps to chromosome 13

PDK2 encodes a member of the pyruvate dehydrogenase kinase family

The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature| suggesting that loss of the DAD1 protein triggered apoptosis

Has no activity towards aliphatic aldehydes and ketones

• Five rotors with 0

Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays The gene encoding ZC3H13 mapsThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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