Human Mitogen Activated Protein Kinase 14, MAPK14 ELISA Kit, 96T Low retention tips In response to BMP ligands|

In response to BMP ligands| this protein can be phosphorylated and activated by the BMP receptor kinase

Mutations in this gene may be associated with Tourette syndrome

The protein encoded by this gene contains two N-terminal doublecortin domains| which bind microtubules and regulate microtubule polymerization| a C-terminal serine/threonine protein kinase domain| which shows substantial homology to Ca2+/calmodulin-dependent protein kinase| and a serine/proline-rich domain in between the doublecortin and the protein kinase domains| which mediates multiple protein-protein interactions

The protein encoded by this gene is a member of the Mastermind-like family of proteins

S-phase kinase-associated protein 2 encoded by this gene belongs to the Fbls class

Human Mitogen Activated Protein Kinase 14, MAPK14 ELISA Kit, 96T Low retention tips In response to BMP ligands|Serine threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may