FA8A Rabbit Polyclonal Antibody, 50ul[BT-AP02610] Proteases This gene is expressed in

This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult

and signal transduction (Hirano et al

The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP)| beta (CEBPB) and may play a role in inflammation

The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related))

It is thought to play a critical role in directing Hsp90 to its target kinases

FA8A Rabbit Polyclonal Antibody, 50ul[BT-AP02610] Proteases This gene is expressed indisease: Defects in F8 are the cause of hemophilia A (HEMA)