PPP1R1C Polyclonal Antibody, 100ul Palm Micro Centrifuges This gene has a pseudogene

This gene has a pseudogene on chromosome 22

The predicted protein contains alpha/beta hydrolase fold and secretory lipase domains

Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines

and negatively regulates the mTOR kinase

This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)

PPP1R1C Polyclonal Antibody, 100ul Palm Micro Centrifuges This gene has a pseudogeneProtein phosphatase 1 (PP1) is a major serine threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al. 2008 [PubMed 18310074]).