LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis and mutations in SLC25A12 may

and mutations in SLC25A12 may also be a cause of global cerebral hypomyelination

This protein and RII PKA colocalize at the cell periphery

The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites| implicating a role in determining and stabilizing dentritic shape during neuron development

which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade

in the chromosome 17q21 region

LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis and mutations in SLC25A12 mayThe protein encoded by this gene is a tumor suppressor with lowered expression levels found in gastric renal colorectal lung and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene.