AAT Monoclonal Antibody, 50ul[BT-MCA0120] Human Genome Knockout Libraries Studies in mice suggest that

Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation

and domains IV and VI have a globular conformation

It is heterogeneously expressed in the brain

The encoded protein is secreted by cells of both the innate and adaptive immune systems

mitotic cycle

AAT Monoclonal Antibody, 50ul[BT-MCA0120] Human Genome Knockout Libraries Studies in mice suggest thatThe protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.