JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates using NADPH to convert estrogens

using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione

in a cluster with two closely related genes which encode similar proteins

Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells

it lacks domain VI

The product of this gene has the lowest sensitivity for these antagonists

JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates using NADPH to convert estrogensThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).