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PP32R1 Polyclonal Antibody, 20ul Peptide Modification Two alternately spliced transcripts encoding

SKU: 35726845246

4.3
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PP32R1 Polyclonal Antibody, 20ul Peptide Modification Two alternately spliced transcripts encodingPhosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. Acidic nuclear phosphoprotein 32 family member C encoded by ANP32C is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been

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Description

Two alternately spliced transcripts encoding two protein isoforms have been identified

one protein-coding and the other not protein-coding

with its amino acid sequence being highly conserved between members and among divergent species

including gene expression

A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes

PP32R1 Polyclonal Antibody, 20ul Peptide Modification Two alternately spliced transcripts encodingPhosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. Acidic nuclear phosphoprotein 32 family member C encoded by ANP32C is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been

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