K1H2 Polyclonal Antibody, 100ul Live Cell Imaging The consequence of CD5 binding

The consequence of CD5 binding to its cognate receptor is still in question and likely plays a role in thymic selection

This gene was originally isolated based on its deletion in a medulloblastoma cell line

Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia

AKR1B1 encodes a member of the aldo/keto reductase superfamily

The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1)

K1H2 Polyclonal Antibody, 100ul Live Cell Imaging The consequence of CD5 bindingThe protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12 q21 and have the same direction of transcription.