Smad3 Polyclonal Antibody, 20ul[BT-AP08391] Transporters 1 is required for the

1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al

This protein is part of a family of structurally and functionally related proteins

are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region

This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner

GADD45G is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents

Smad3 Polyclonal Antibody, 20ul[BT-AP08391] Transporters 1 is required for theThe protein encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of