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Peroxin 10 Polyclonal Antibody, 50ul Immunoassays FOX transcription factors are characterized

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Peroxin 10 Polyclonal Antibody, 50ul Immunoassays FOX transcription factors are characterizedPEX10 (peroxisomal biogenesis factor 10) encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in PEX10 result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms.

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Description

FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism

Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma

which is a member of the X family of DNA polymerases

and trithorax) domain

The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility

Peroxin 10 Polyclonal Antibody, 50ul Immunoassays FOX transcription factors are characterizedPEX10 (peroxisomal biogenesis factor 10) encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in PEX10 result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms.

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