CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes suggesting a distinct role for

suggesting a distinct role for this antizyme in spermiogenesis

Three alternatively spliced variants encoding different isoforms have been described for this gene

The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA

except for testis

where disruption of the gene for that protein had no observable phenotype

CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes suggesting a distinct role forDDIT3 encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. DNA damage inducible transcript 3 functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.