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Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy It contains extracellular kringle

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy It contains extracellular kringle

Name: Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy It contains extracellular kringle
Brand: clickpoint.com.au
SKU: 36611700212
Price: 142.00 USD
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Rating: 4.6633 (23 reviews)

SKU: 36611700212

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Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy It contains extracellular kringleThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.

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Description

It contains extracellular kringle

Another member of the CHP subfamily

It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro

thymus and fetal liver

Widely expressed in fetal tissues

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