ER Alpha Monoclonal Antibody, 100ul[BT-MCA0515] Antibody Development and undergoes ubiquitination and proteasome-mediated

and undergoes ubiquitination and proteasome-mediated degradation

indicating a role as a negative regulator of CDC2/cyclin A

The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes

Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3)

The product of this gene has the lowest sensitivity for these antagonists

ER Alpha Monoclonal Antibody, 100ul[BT-MCA0515] Antibody Development and undergoes ubiquitination and proteasome-mediatedThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen