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JAM-B Polyclonal Antibody, 20ul Site-directed Mutagenesis The intracellular cytoplasmic tail of

SKU: 36999449188

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JAM-B Polyclonal Antibody, 20ul Site-directed Mutagenesis The intracellular cytoplasmic tail ofJAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript

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Description

The intracellular cytoplasmic tail of this protein has been found to interact with moesin

The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis

LIR family members are known to have activating and inibitory functions in leukocytes

CD47 encodes a CD47 molecule

and dysequilibrium syndrome 3 (CMARQ3)

JAM-B Polyclonal Antibody, 20ul Site-directed Mutagenesis The intracellular cytoplasmic tail ofJAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript

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