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A number of genetic diseases are linked to genes on chromosome 2

This gene is intronless

and in mitotic checkpoint signaling

Catenin- Alpha E/N Polyclonal Antibody, 20ul Dry Bath Get ready for accurate andCTNNA1 encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein (catenin alpha 1) contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin actin filament connections. Certain