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BRCA1(Phospho Ser988) Rabbit Polyclonal Antibody, 50ul Variant Libraries The encoded enzyme binds to

SKU: 38629343140

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BRCA1(Phospho Ser988) Rabbit Polyclonal Antibody, 50ul Variant Libraries The encoded enzyme binds todisease: Defects in BRCA1 are a cause of genetic susceptibility to breast cancer (BC)

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Description

The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor

The encoded protein is associated with the nuclear scaffold in proliferating cells| and binds to actin and the catalytic subunit of protein phosphatase-1| suggesting that it functions as a regulatory subunit of protein phosphatase-1

The ficolin family of proteins are characterized by the presence of a leader peptide

The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion

trichoepitheliomas

BRCA1(Phospho Ser988) Rabbit Polyclonal Antibody, 50ul Variant Libraries The encoded enzyme binds todisease: Defects in BRCA1 are a cause of genetic susceptibility to breast cancer (BC)

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