Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing subcellular location:Expressed diffusely throughout the

subcellular location:Expressed diffusely throughout the nucleus

Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly

Translocations between MLF1 and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia

The protein may also be involved in the pathophysiology of depression

it is now thought to be a non-opioid receptor

Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing subcellular location:Expressed diffusely throughout theThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.