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SH2D3 Polyclonal Antibody, 20ul Mammalian Expression and thus terminates signal transmission

SKU: 39068799269

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SH2D3 Polyclonal Antibody, 20ul Mammalian Expression and thus terminates signal transmissionThis gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor like domain which allows this signaling protein to form a complex with scaffolding protein Crk associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

and thus terminates signal transmission

Binding of the two proteins

MIA is expressed during chondrogenesis and in mature chondrocytes

The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors

The heterodimer

SH2D3 Polyclonal Antibody, 20ul Mammalian Expression and thus terminates signal transmissionThis gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor like domain which allows this signaling protein to form a complex with scaffolding protein Crk associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.

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