PARP9 Polyclonal Antibody, 50ul Low retention tips Alternative splicing results in at

Alternative splicing results in at least two different transcript variants

This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL)

The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription

and caspase 10

Two pseudogenes of this gene have been identified within this cluster on chromosome 7

PARP9 Polyclonal Antibody, 50ul Low retention tips Alternative splicing results in atCatalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,miscellaneous: Overexpressed at significantly higher levels in fatal high risk diffuse large B cell lymphomas (DLB CL) compared to cured low risk tumors. Overexpression in B cell lymphoma transfectants may promote malignant B cell migration.,Contains 1 PARP catalytic domain.,Contains 2 Macro domains.,subunit: Interacts with BBAP.,tissue