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PFKM Polyclonal Antibody, 50ul CellSafe™ This gene product binds to

SKU: 39246656514

4.8
USD162.00 USD183.00

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PFKM Polyclonal Antibody, 50ul CellSafe™ This gene product binds toThree phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose 6 phosphate to fructose 1,6 bisphosphate. Tetramer composition varies depending on tissue type. PFKM encodes the muscle type isozyme. Mutations in PFKM have been associated with glycogen storage disease type VII, also known as Tarui disease.

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Description

This gene product binds to and inactivates p38 and SAPK/JNK

it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins

suggesting that this protein may act as a regulator of TGIF2LX

Microtubules maintain cellular structure

The encoded mechanosensing protein (catenin alpha 1) contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension

PFKM Polyclonal Antibody, 50ul CellSafe™ This gene product binds toThree phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose 6 phosphate to fructose 1,6 bisphosphate. Tetramer composition varies depending on tissue type. PFKM encodes the muscle type isozyme. Mutations in PFKM have been associated with glycogen storage disease type VII, also known as Tarui disease.

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