PA26 Polyclonal Antibody, 100ul Serological Pipets Tie-1 and tek/tie-2 define a

Tie-1 and tek/tie-2 define a new class of RTKs containing two immunoglobulin-like domains

It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs)

Multiple pseudogenes of this gene are located on chromosome 1

encoding the same protein

which function in various biological processes including axon guidance

PA26 Polyclonal Antibody, 100ul Serological Pipets Tie-1 and tek/tie-2 define aSESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized