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ATP-citrate synthase Monoclonal Antibody, 100ul Electronic Pipette A mutation in this gene

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ATP-citrate synthase Monoclonal Antibody, 100ul Electronic Pipette A mutation in this geneATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

A mutation in this gene was found in individuals with dementia with Lewy bodies

COL13A1 encodes the alpha chain of one of the nonfibrillar collagens

Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol

Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals

Diseases associated with SUPT3H include blastic plasmacytoid dendritic cell

ATP-citrate synthase Monoclonal Antibody, 100ul Electronic Pipette A mutation in this geneATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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