RGDSR Polyclonal Antibody, 20ul In vitro Transcription Defects in this gene are

Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease

The protein encoded by this gene belongs to the protein kinase C superfamily

Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression

Alternatively spliced variants encoding different isoforms have been identified

identified in the human major histocompatibility complex class I region

RGDSR Polyclonal Antibody, 20ul In vitro Transcription Defects in this gene areThis oncogene encodes a protein similar to guanine nucleotide exchange factor Ral guanine dissociation stimulator. Increased expression of this gene leads to translocation of the encoded protein to the cell membrane. The encoded protein can activate several pathways, including the Ras Raf MEK ERK cascade.