TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 100ul Serological Pipets VitroGel ORGANOID-2

VitroGel ORGANOID-2

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction

The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding

This kinase is involved in the regulation of protein synthesis

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 100ul Serological Pipets VitroGel ORGANOID-2Catalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only