DYRK3 Polyclonal Antibody, 20ul Custom DNA Oligos Genomic sequences representing several pseudogenes

Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene

Mutation of this gene is associated with acute myeloid leukemia

DAP (death associated protein) kinase and ZIP kinase are members of a novel protein kinase family

tissue specificity:Expressed abundantly in the lung and neutrophils

JUP encodes a major cytoplasmic protein (junction plakoglobin) which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions

DYRK3 Polyclonal Antibody, 20ul Custom DNA Oligos Genomic sequences representing several pseudogenesThis gene product belongs to the DYRK family of dual specificity protein kinases that catalyze autophosphorylation on serine threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in