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CD55 Polyclonal Antibody, 50ul[BT-AP02079] Vacuum Aspirator MAD2 is a key component

SKU: 40222146867

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CD55 Polyclonal Antibody, 50ul[BT-AP02079] Vacuum Aspirator MAD2 is a key componentCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology

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Description

MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle

Mutations in this gene have been associated with several diseases

leading to the dephosphorylation of Cdc2 in the late G2 phase

WEE1 (WEE1 G2 checkpoint kinase) encodes a nuclear protein

constituting the KDEL receptor gene family

CD55 Polyclonal Antibody, 50ul[BT-AP02079] Vacuum Aspirator MAD2 is a key componentCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology

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