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EAA2 Rabbit Polyclonal Antibody, 20ul Filtration NUSAP1 is a nucleolar-spindle-associated protein

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EAA2 Rabbit Polyclonal Antibody, 20ul Filtration NUSAP1 is a nucleolar-spindle-associated proteinThis gene encodes a member of a family of solute transporter proteins. The membrane bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are

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Description

NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al

This gene encodes a member of the doublecortin family

the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation

Does not inhibit type-2 phosphatases

EAA2 Rabbit Polyclonal Antibody, 20ul Filtration NUSAP1 is a nucleolar-spindle-associated proteinThis gene encodes a member of a family of solute transporter proteins. The membrane bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are

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