PEG3 Polyclonal Antibody, 100ul Cell Culture Dishes The protein is weakly similar

The protein is weakly similar to transposase-like proteins in human and mouse

and is able to complement the yeast cdc42-1 mutant

This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen

Mutations in this gene have also been associated with breast tumor development

An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome

PEG3 Polyclonal Antibody, 100ul Cell Culture Dishes The protein is weakly similarIn human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID: 15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2