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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies This protein interacts with polycystin

SKU: 41156754948

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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies This protein interacts with polycystinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

This protein interacts with polycystin 1

and in the renal tubular response to proteinuria

for quality traceability

This gene and FGF3

Mutations in GDI1 have been linked to X-linked nonspecific mental retardation

Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies This protein interacts with polycystinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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