GDF-6 Polyclonal Antibody, 50ul Biochemical Reagents elegans gene UNC-51 in which

elegans gene UNC-51 in which mutants exhibited abnormal axonal extension and growth

|PTM:Tyrosine phosphorylated in response to IFN-alpha

which suggests a role in the JNK signaling pathway

This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs)

and a tail domain that serves as an anchor

GDF-6 Polyclonal Antibody, 50ul Biochemical Reagents elegans gene UNC-51 in whichGDF6 encodes a member of the bone morphogenetic protein (BMP) family and the TGF beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.