Survivin Polyclonal Antibody, 100ul[BT-AP01683] Peripheral Blood Separation Tube Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been found for EIF2B3

The protein localizes to the endoplasmic reticulum (ER)

and also in the phagocytosis of complement coated particles

suggesting implicit roles in reproduction

Jervell and Lange-Nielsen syndrome

Survivin Polyclonal Antibody, 100ul[BT-AP01683] Peripheral Blood Separation Tube Alternatively spliced transcript variants encodingThis gene is a member of the inhibitor of apoptosis (IAP) gene family which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues.