Rat Glucagon-like Peptide 1 Receptor, GLP1R ELISA Kit, 96T Peptide Library May mediate homophilic as well

May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain

MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8

and poly(ADP-ribose) polymerase (PARP) cleavage

thus reducing the breakdown of stalled replication forks and avoiding DNA damage (PubMed: 20493174)

Ubiquitinates p53 independently of MDM2 or RCHY1

Rat Glucagon-like Peptide 1 Receptor, GLP1R ELISA Kit, 96T Peptide Library May mediate homophilic as wellG protein coupled receptor for glucagon like Peptide 1 (GLP 1) (PubMed: 1326760, PubMed: 7813606). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed: 1326760, PubMed: 7813606). Plays a role in regulating insulin secretion in response to GLP 1 (By similarity).