EVX2 Rabbit Polyclonal Antibody, 100ul Protein Research It is a single span

It is a single span type I transmembrane protein that contains a 484 aa extracellular region (aa 31‑514) plus a 68 aa C‑terminal cytoplasmic domain

Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS)

Abnormal recombination between PRKX and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins

ThAKAP8 encodes a nuclear A-kinase anchor protein (A-kinase anchoring protein 8) that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin

EVX2 Rabbit Polyclonal Antibody, 100ul Protein Research It is a single spanThis gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even skipped (eve) gene a member of the pair rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster which includes this gene and the HOXD9 HOXD13 genes causes synpolydactyly a dominantly inherited disease resulting in limb