P53 Polyclonal Antibody, 20ul[BT-AP06811] Pipette Controller The extracellular domain of NG2

The extracellular domain of NG2 sequesters growth factors and binds to both growth factor receptors and extracellular matrix ligands such as fibronectin

encodes a G protein-coupled receptor

This member contains a nuclear targeting signal sequence

including blood group ABH antigens and developmental adhesion antigens

Multiple alternatively spliced transcript variants encoding different isoforms have been identified

P53 Polyclonal Antibody, 20ul[BT-AP06811] Pipette Controller The extracellular domain of NG2TP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni