AP2A Polyclonal Antibody, 50ul Oligo Pool The gene encoding CYB561D2 maps

The gene encoding CYB561D2 maps to human chromosome 3p21

By itself| the protein has 3' to 5' exonuclease activity and endonuclease activity

Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0

Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera

|PTM:While translation occurs| the particular unfolded structure after the GRR repeat promotes the generation of p50 making it an acceptable substrate for the proteasome

AP2A Polyclonal Antibody, 50ul Oligo Pool The gene encoding CYB561D2 mapsThe protein encoded by this gene is a transcription factor that binds the consensus sequence 5' GCCNNNGGC 3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found