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p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody, 20ul Shakers Most Caucasians have two major

SKU: 43130390643

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p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody, 20ul Shakers Most Caucasians have two majorThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1

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Description

Most Caucasians have two major isozymes

Produced as a single chain precursor

Multiple transcript variants encoding different isoforms have been found for CLK1

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid

p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody, 20ul Shakers Most Caucasians have two majorThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1

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