TPH1 Polyclonal Antibody, 50ul[BT-AP09150] Enzyme Activity Assays Mutations in CDKN1C are implicated

Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome

IP6K3 encodes a protein that belongs to the inositol phosphokinase (IPK) family

A related pseudogene has been identified on chromosome 17

resulting in the creation of an N-terminal chain and the corresponding C-terminal chain

Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome

TPH1 Polyclonal Antibody, 50ul[BT-AP09150] Enzyme Activity Assays Mutations in CDKN1C are implicatedTPH1 (tryptophan hydroxylase 1) encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and