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IL-13R alpha 1(Phospho Tyr405) Polyclonal Antibody, 20ul Buffer Solutions Multiple alternatively spliced transcript variants

SKU: 43339520645

4.6
SEK111.00 SEK133.00

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IL-13R alpha 1(Phospho Tyr405) Polyclonal Antibody, 20ul Buffer Solutions Multiple alternatively spliced transcript variantsThe protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13 binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3

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Description

Multiple alternatively spliced transcript variants encoding different isoforms have been observed for MOK

like most family members

However| this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus| and a transposase domain at the C-terminus| suggesting that it may belong to the family of DNA-mediated transposons in human

The gene is deleted in Williams-Beuren syndrome| a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11

Prostaglandin E receptor 3 encoded by PTGER3 is a member of the G-protein coupled receptor family

IL-13R alpha 1(Phospho Tyr405) Polyclonal Antibody, 20ul Buffer Solutions Multiple alternatively spliced transcript variantsThe protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13 binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3

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