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Socius Polyclonal Antibody, 50ul Molecular Weight Markers This gene encodes a member

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Socius Polyclonal Antibody, 50ul Molecular Weight Markers This gene encodes a memberUBXN11 (UBX domain protein 11) encodes a protein with a divergent C terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C terminal region. It also interacts with several heterotrimeric G proteins through their G alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity

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Description

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate

The core structure is composed of 4 rings of 28 non-identical subunits

The protein binds to RNA via two KH domains and also colocalizes with MEX3A| Dcp1A decapping factor and Argonaute proteins within P (processing) bodies

recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin

mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis

Socius Polyclonal Antibody, 50ul Molecular Weight Markers This gene encodes a memberUBXN11 (UBX domain protein 11) encodes a protein with a divergent C terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C terminal region. It also interacts with several heterotrimeric G proteins through their G alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity

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