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Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage Two transcript variants encoding different

SKU: 43664805198

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Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage Two transcript variants encoding differentThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Two transcript variants encoding different isoforms have been found for RAC1

Some members of this protein family may play a role in apoptosis

In spite of the structural and functional differences

CHD1L encodes a DNA helicase protein involved in DNA repair

Hirschsprung disease type 2

Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage Two transcript variants encoding differentThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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