Mnk1(Phospho Thr250) Polyclonal Antibody, 50ul Monoclonal Antibodies The leucine zipper down-regulated in

The leucine zipper down-regulated in cancer 1 encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain

Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons

A similar protein in mouse binds E12| a transcriptional regulator of immunoglobulin genes

Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia

both of which are involved in UV radiation induced apoptosis

Mnk1(Phospho Thr250) Polyclonal Antibody, 50ul Monoclonal Antibodies The leucine zipper down-regulated inThis gene encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.