AP-1 Polyclonal Antibody, 50ul[BT-AP00488] Vacuum Aspirator Four members of this family

Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080)| LYL1 (MIM 151440)| E2A (MIM 147141)| and SCL (MIM 187040)

and is also thought to be critical for mesoderm formation in the developing embryo

suggesting that this is one of the oldest cytochrome P450 genes

The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3

FZD4 (frizzled class receptor 4) is a member of the frizzled gene family

AP-1 Polyclonal Antibody, 50ul[BT-AP00488] Vacuum Aspirator Four members of this familyJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.