SH2B3 Polyclonal Antibody, 50ul Buffer Solutions High affinity receptor for urotensin-2

High affinity receptor for urotensin-2 and urotensin-2B

Type I and II receptors form a stable complex after ligand binding| resulting in phosphorylation of type I receptors by type II receptors

The encoded gene product presumably interacts with YY1 protein

and may be involved in pancreatic lithogenesis

The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily

SH2B3 Polyclonal Antibody, 50ul Buffer Solutions High affinity receptor for urotensin-2This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced