Shh Monoclonal Antibody, 100ul Antibody Development It is induced by heat

It is induced by heat shock and treatment with the HSP 90 inhibitor 17-demeth-oxygeldanamycin

This protein and ATM share similarity with Schizosaccharomyces pombe rad3

Mutations in this gene cause familial cold autoinflammatory syndrome type 2

Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease

and an integral membrane V(0) domain for proton translocation

Shh Monoclonal Antibody, 100ul Antibody Development It is induced by heatThis gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved the N